The paper examined the effect of corporate social responsibility on the performance of Nigerian deposit money banks with special reference to Guarantee Trust Bank PLC in Nigeria (GTBank). The paper made positions that corporate social responsibility enhances the performance of banks. Hence, we empirically examined the impact of corporate social responsibility on profit of GTBank for the period 2006 till 2018. From the model specified, the unit root test indicated that the result was stationary at level showing there is a long run co-integration among the variables. The result of the OLS result showed that there was a positive and significant impact of corporate social responsibility on the profit performance of GTBank. We therefore recommend that all stakeholders should ensure that they encourage their banks to have serious commitment towards corporate social responsibility as this has added value to their investment in the long run.